Psychological impacts of PCOS

The popularity of depression in PCOS is high .Depressive symptoms and mood disorders are common in most obese patients. However, there is varying information about the effects of obesity on risks of depression. Adali et al. showed that BMI and waist-to-hip ratio (WHR) were significantly greater in patients with PCOS, for whom results also showed highly elevated emotional distress and depression compared to the control group. Obesity may be a risk factor for psychological distress and depression in patients with PCOS.

Depression has been coordinated with increased cortisol levels, increased sympathetic activity and decreased serotonin levels in the central nervous system, features also associated with insulin resistance. Depression is about twice as common in people with diabetes compared with healthy individuals and treating depression can improve glucose control, although this is not a consistent finding. Diabetes is also a risk factor psychological distress and depression in patients with PCOS.