Fertilization is the process of combining male gamete and female gamete which results in the formation of zygote in 10% of male suffering from infertility with Spermatogenesis disorder due to drastic alteration in their lifestyle, surroundings or environmental factors and Hormonal imbalances most of the couple i.e., 17.2% couple in 30% are not supposed to have a child. There are numerous reasons to evaluate that causing infertility either in male or female of that certain couple. To get fertile various modern inventive techniques has been introduced. Since these methods are based on the steps or procedure of in vitro improvement in Semen quality to over the natural barrier of fertilization. Techniques include various processes on their own specific indications.