Treatment of PCOS disorder should focus on reduction of androgen-associated symptoms, the protection of the endometrium, and reduction of the long-term risks of diabetes and cardiovascular complications. For many women with this syndrome, improving infertility is a primary goal of therapy. Nurse-midwives can assess and manage many of the presenting complaints and lifestyle issues, such as menstrual disorders, hirsutism, and obesity, which are associated with PCOS. The nurse-midwife may choose to manage the more complex problems, such as infertility and insulin resistance, in collaboration with a gynecologist or endocrinologist. It is imperative that we act to prevent the far-reaching consequences of this syndrome.